Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure

Carboplatin-paclitaxel is a reference regimen in the treatment of locally advanced or disseminated non-small cell lung cancer (NSCLC). This paper discusses the multidrug resistance developed with this drug combination, which is one of the major obstacles to successful treatment. In order to understa...

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Bibliografiske detaljer
Main Authors: Melguizo, Consolación, Prados, Jose, Luque, Raquel, Ortiz, Raúl, Caba, Octavio, Álvarez, Pablo J., Gonzalez, Beatriz, Aranega, Antonia
Format: Artigo
Sprog:Inglês
Udgivet: Molecular Diversity Preservation International (MDPI) 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546711/
https://ncbi.nlm.nih.gov/pubmed/23443122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131216624
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