Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure

Carboplatin-paclitaxel is a reference regimen in the treatment of locally advanced or disseminated non-small cell lung cancer (NSCLC). This paper discusses the multidrug resistance developed with this drug combination, which is one of the major obstacles to successful treatment. In order to understa...

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Detalhes bibliográficos
Main Authors: Consolación Melguizo, Jose Prados, Raquel Luque, Raúl Ortiz, Octavio Caba, Pablo J. Álvarez, Beatriz Gonzalez, Antonia Aranega
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-12-01
Colecção:International Journal of Molecular Sciences
Assuntos:
lung cancer
resistance
MDR
MRP
paclitaxel
carboplatin
Acesso em linha:http://www.mdpi.com/1422-0067/13/12/16624
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