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Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives

Patients with cancer have an impaired T-cell response that can decrease the potential therapeutic benefit of cancer vaccines and other forms of immunotherapy. l-arginine (l-Arg) is a conditionally essential amino acid that is fundamental for the function of T lymphocytes. Recent findings in tumor-be...

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Detalhes bibliográficos
Main Authors: Rodríguez, Paulo C., Ochoa, Augusto C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3546504/
https://ncbi.nlm.nih.gov/pubmed/18364002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2008.00608.x
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