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Protection from superoxide damage associated with an increased level of the YggX protein in Salmonella enterica

The deleterious effect of superoxide radicals on cell growth and survival is predominately caused by rapid oxidation of labile [Fe-S] clusters in proteins. Oxidation of these clusters releases Fe(II) ions, which participate in Fenton chemistry that damages DNA. Here it is shown that elevated levels...

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Библиографические подробности
Главные авторы: Gralnick, Jeffrey, Downs, Diana
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2001
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC35462/
https://ncbi.nlm.nih.gov/pubmed/11416172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151243198
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