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Protection from superoxide damage associated with an increased level of the YggX protein in Salmonella enterica

The deleterious effect of superoxide radicals on cell growth and survival is predominately caused by rapid oxidation of labile [Fe-S] clusters in proteins. Oxidation of these clusters releases Fe(II) ions, which participate in Fenton chemistry that damages DNA. Here it is shown that elevated levels...

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Autori principali: Gralnick, Jeffrey, Downs, Diana
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC35462/
https://ncbi.nlm.nih.gov/pubmed/11416172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151243198
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