Protection from superoxide damage associated with an increased level of the YggX protein in Salmonella enterica
The deleterious effect of superoxide radicals on cell growth and survival is predominately caused by rapid oxidation of labile [Fe-S] clusters in proteins. Oxidation of these clusters releases Fe(II) ions, which participate in Fenton chemistry that damages DNA. Here it is shown that elevated levels...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416172/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151243198 |
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