Diacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release

Diacylglycerol acyltransferase-1 (DGAT1) is a potential therapeutic target for treatment of obesity and related metabolic diseases. However, the degree of DGAT1 inhibition required for metabolic benefits is unclear. Here we show that partial DGAT1 deficiency in mice suppressed postprandial triglycer...

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Autors principals: Lin, Hua V., Chen, Dunlu, Shen, Zhu, Zhu, Lei, Ouyang, Xuesong, Vongs, Aurawan, Kan, Yanqing, Levorse, John M., Kowalik, Edward J., Szeto, Daphne M., Yao, Xiaorui, Xiao, Jianying, Chen, Shirley, Liu, Jinqi, Garcia-Calvo, Marga, Shin, Myung K., Pinto, Shirly
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545956/
https://ncbi.nlm.nih.gov/pubmed/23336002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054480
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