Diacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release

Diacylglycerol acyltransferase-1 (DGAT1) is a potential therapeutic target for treatment of obesity and related metabolic diseases. However, the degree of DGAT1 inhibition required for metabolic benefits is unclear. Here we show that partial DGAT1 deficiency in mice suppressed postprandial triglycer...

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Главные авторы: Lin, Hua V., Chen, Dunlu, Shen, Zhu, Zhu, Lei, Ouyang, Xuesong, Vongs, Aurawan, Kan, Yanqing, Levorse, John M., Kowalik, Edward J., Szeto, Daphne M., Yao, Xiaorui, Xiao, Jianying, Chen, Shirley, Liu, Jinqi, Garcia-Calvo, Marga, Shin, Myung K., Pinto, Shirly
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545956/
https://ncbi.nlm.nih.gov/pubmed/23336002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054480
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