Diacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release

Diacylglycerol acyltransferase-1 (DGAT1) is a potential therapeutic target for treatment of obesity and related metabolic diseases. However, the degree of DGAT1 inhibition required for metabolic benefits is unclear. Here we show that partial DGAT1 deficiency in mice suppressed postprandial triglycer...

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Detalhes bibliográficos
Main Authors: Lin, Hua V., Chen, Dunlu, Shen, Zhu, Zhu, Lei, Ouyang, Xuesong, Vongs, Aurawan, Kan, Yanqing, Levorse, John M., Kowalik, Edward J., Szeto, Daphne M., Yao, Xiaorui, Xiao, Jianying, Chen, Shirley, Liu, Jinqi, Garcia-Calvo, Marga, Shin, Myung K., Pinto, Shirly
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545956/
https://ncbi.nlm.nih.gov/pubmed/23336002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054480
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