Diacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release

Diacylglycerol acyltransferase-1 (DGAT1) is a potential therapeutic target for treatment of obesity and related metabolic diseases. However, the degree of DGAT1 inhibition required for metabolic benefits is unclear. Here we show that partial DGAT1 deficiency in mice suppressed postprandial triglycer...

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Détails bibliographiques
Auteurs principaux: Lin, Hua V., Chen, Dunlu, Shen, Zhu, Zhu, Lei, Ouyang, Xuesong, Vongs, Aurawan, Kan, Yanqing, Levorse, John M., Kowalik, Edward J., Szeto, Daphne M., Yao, Xiaorui, Xiao, Jianying, Chen, Shirley, Liu, Jinqi, Garcia-Calvo, Marga, Shin, Myung K., Pinto, Shirly
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545956/
https://ncbi.nlm.nih.gov/pubmed/23336002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054480
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