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Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders

BACKGROUND: Adeno-associated virus (AAV) is well established as a vehicle for in vivo gene transfer into the mammalian retina. This virus is promising not only for gene therapy of retinal diseases, but also for in vivo functional analysis of retinal genes. Previous reports have shown that AAV can in...

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Hlavní autoři: Watanabe, Satoshi, Sanuki, Rikako, Ueno, Shinji, Koyasu, Toshiyuki, Hasegawa, Toshiaki, Furukawa, Takahisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545928/
https://ncbi.nlm.nih.gov/pubmed/23335994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054146
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