Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders

BACKGROUND: Adeno-associated virus (AAV) is well established as a vehicle for in vivo gene transfer into the mammalian retina. This virus is promising not only for gene therapy of retinal diseases, but also for in vivo functional analysis of retinal genes. Previous reports have shown that AAV can in...

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Main Authors: Watanabe, Satoshi, Sanuki, Rikako, Ueno, Shinji, Koyasu, Toshiyuki, Hasegawa, Toshiaki, Furukawa, Takahisa
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545928/
https://ncbi.nlm.nih.gov/pubmed/23335994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054146
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