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Tropisms of AAV for Subretinal Delivery to the Neonatal Mouse Retina and Its Application for In Vivo Rescue of Developmental Photoreceptor Disorders

BACKGROUND: Adeno-associated virus (AAV) is well established as a vehicle for in vivo gene transfer into the mammalian retina. This virus is promising not only for gene therapy of retinal diseases, but also for in vivo functional analysis of retinal genes. Previous reports have shown that AAV can in...

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Detalhes bibliográficos
Main Authors: Watanabe, Satoshi, Sanuki, Rikako, Ueno, Shinji, Koyasu, Toshiyuki, Hasegawa, Toshiaki, Furukawa, Takahisa
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545928/
https://ncbi.nlm.nih.gov/pubmed/23335994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054146
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