HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold

The HIV-1 Tat protein stimulates viral gene expression by recruiting human transcription elongation complexes containing P-TEFb, AFF4, ELL2, and ENL or AF9 to the viral promoter, but the molecular organization of these complexes remains unknown. To establish the overall architecture of the HIV-1 Tat...

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Detalhes bibliográficos
Main Authors: Chou, Seemay, Upton, Heather, Bao, Katherine, Schulze-Gahmen, Ursula, Samelson, Avi J., He, Nanhai, Nowak, Anna, Lu, Huasong, Krogan, Nevan J., Zhou, Qiang, Alber, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545800/
https://ncbi.nlm.nih.gov/pubmed/23251033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216971110
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