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Catalytic consumption of nitric oxide by 12/15- lipoxygenase: Inhibition of monocyte soluble guanylate cyclase activation
12/15-Lipoxygenase (LOX) activity is elevated in vascular diseases associated with impaired nitric oxide ((⋅)NO) bioactivity, such as hypertension and atherosclerosis. In this study, primary porcine monocytes expressing 12/15-LOX, rat A10 smooth muscle cells transfected with murine 12/15-LOX, and pu...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The National Academy of Sciences
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC35458/ https://ncbi.nlm.nih.gov/pubmed/11427723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141136098 |
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