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Deletion of Mthfd1l causes embryonic lethality and neural tube and craniofacial defects in mice
Maternal supplementation with folic acid is known to reduce the incidence of neural tube defects (NTDs) by as much as 70%. Despite the strong clinical link between folate and NTDs, the biochemical mechanisms through which folic acid acts during neural tube development remain undefined. The Mthfd1l g...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545794/ https://ncbi.nlm.nih.gov/pubmed/23267094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211199110 |
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