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Deletion of neural tube defect-associated gene Mthfd1l causes reduced cranial mesenchyme density

BACKGROUND: Periconceptional intake of supplemental folic acid can reduce the incidence of neural tube defects by as much as 70%, but the mechanisms by which folic acid supports cellular processes during neural tube closure are unknown. The mitochondrial 10-formyl-tetrahydrofolate synthetase MTHFD1L...

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Detalhes bibliográficos
Publicado no:Birth Defects Res
Main Authors: Shin, Minhye, Vaughn, Amanda, Momb, Jessica, Appling, Dean R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939463/
https://ncbi.nlm.nih.gov/pubmed/31518072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdr2.1591
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