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α2 and α3 helices of dystrophin R16 and R17 frame a microdomain in the α1 helix of dystrophin R17 for neuronal NOS binding

Homologous spectrin-like repeats can mediate specific protein interaction. The underlying mechanism is poorly understood. Dystrophin contains 24 spectrin-like repeats. However, only repeats 16 and 17 (R16/17) are required for anchoring neuronal NOS (nNOS) to the sarcolemma. Through an adeno-associat...

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Hlavní autoři: Lai, Yi, Zhao, Junling, Yue, Yongping, Duan, Dongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545791/
https://ncbi.nlm.nih.gov/pubmed/23185009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211431109
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