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Nitrosative stress elicited by nNOSμ delocalization inhibits muscle force in dystrophin-null mice

The mechanism of force reduction is not completely understood in Duchenne muscular dystrophy (DMD), a dystrophin-deficient lethal disease. Nitric oxide regulates muscle force. Interestingly, neuronal nitric oxide synthase μ (nNOSμ), a major source of muscle nitric oxide, is lost from the sarcolemma...

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Detalhes bibliográficos
Main Authors: Li, Dejia, Yue, Yongping, Lai, Yi, Hakim, Chady H, Duan, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109084/
https://ncbi.nlm.nih.gov/pubmed/21125668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2799
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