Sarcolemmal nNOS anchoring reveals a qualitative difference between dystrophin and utrophin

Duchenne muscular dystrophy (DMD) is a lethal muscle disease caused by dystrophin deficiency. In normal muscle, dystrophin helps maintain sarcolemmal stability. Dystrophin also recruits neuronal nitric oxide synthase (nNOS) to the sarcolemma. Failure to anchor nNOS to the membrane leads to functiona...

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Bibliografiset tiedot
Päätekijät: Li, Dejia, Bareja, Akshay, Judge, Luke, Yue, Yongping, Lai, Yi, Fairclough, Rebecca, Davies, Kay E., Chamberlain, Jeffrey S., Duan, Dongsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Company of Biologists 2010
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880012/
https://ncbi.nlm.nih.gov/pubmed/20483958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.064808
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