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Conformational Equilibrium of N-Myristoylated cAMP-Dependent Protein Kinase A by Molecular Dynamics Simulations
The catalytic subunit of protein kinase A (PKA-C) is subject to several post- or co-translational modifications that regulate its activity both spatially and temporally. Among those, N-myristoylation increases the kinase affinity for membranes and might also be implicated in substrate recognition an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3545707/ https://ncbi.nlm.nih.gov/pubmed/23205665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301279f |
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