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ALLN rescues an in vitro excitatory synaptic transmission deficit in Lis1 mutant mice

LIS1 gene mutations lead to a rare neurological disorder, classical lissencephaly, characterized by brain malformations, mental retardation, seizures, and premature death. Mice heterozygous for Lis1 (Lis1(+/−)) exhibit cortical malformations, defects in neuronal migration, increased glutamate-mediat...

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Détails bibliographiques
Auteurs principaux: Sebe, Joy Y., Bershteyn, Marina, Hirotsune, Shinji, Wynshaw-Boris, Anthony, Baraban, Scott C.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545457/
https://ncbi.nlm.nih.gov/pubmed/23100132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00431.2012
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