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The effect of imatinib mesylate on the proliferation, invasive ability, and radiosensitivity of retinoblastoma cell lines

PURPOSE: Our aim was to evaluate the potential effect of imatinib mesylate (IM), a small molecule that specifically inhibits the tyrosine quinase receptors, on the proliferation and invasive abilities of two human retinoblastoma (Rb) cell lines. Furthermore, the ability of IM to radiosensitize Rb ce...

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Détails bibliographiques
Auteurs principaux: de Moura, L R, Marshall, J-C, Di Cesare, S, Fernandes, B F, Antecka, E, Burnier, M N
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545385/
https://ncbi.nlm.nih.gov/pubmed/23154488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2012.231
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