In vitro effects of imatinib mesylate on radiosensitivity and chemosensitivity of breast cancer cells

BACKGROUND: Breast cancer treatment is based on a combination of adjuvant chemotherapy followed by radiotherapy effecting intracellular signal transduction. With the tyrosine kinase inhibitors new targeted drugs are available. Imatinib mesylate is a selective inhibitor of bcr-abl, PRGFR alpha, beta...

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Hlavní autoři: Weigel, Marion T, Dahmke, Linda, Schem, Christian, Bauerschlag, Dirk O, Weber, Katrin, Niehoff, Peter, Bauer, Maret, Strauss, Alexander, Jonat, Walter, Maass, Nicolai, Mundhenke, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925350/
https://ncbi.nlm.nih.gov/pubmed/20691121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-412
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