Imatinib Mesylate Alters the Expression of Genes Related to Disease Progression in an Animal Model of Uveal Melanoma

Imatinib mesylate (IM) is a compound that inhibits both BCR-ABL tyrosine kinase and c-kit receptors. Tyrosine kinases are important in cellular signaling and mediate major cellular processes such as proliferation, differentiation, apoptosis, attachment, and migration. Twenty-six albino rabbits were...

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Publicat a:Anal Cell Pathol (Amst)
Autors principals: Fernandes, Bruno F., Di Cesare, Sebastian, Belfort, Rubens Neto, Maloney, Shawn, Martins, Claudia, Castiglione, Enzo, Isenberg, Jordan, Abourbih, Daniel, Antecka, Emilia, Burnier Jr., Miguel N.
Format: Artigo
Idioma:Inglês
Publicat: IOS Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4605589/
https://ncbi.nlm.nih.gov/pubmed/21606571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/ACP-2011-0010
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