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HLA Class II Molecules Influence Susceptibility vs Protection in Inflammatory Diseases by Determining the Cytokine Profile

The MHC in humans encodes the most polymorphic genes, the HLA genes, which are critical for the immune system to clear infection. This can be attributed to strong selection pressure as populations moved to different parts of the world and encountered new kinds of infections, leading to new HLA class...

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Auteurs principaux: Mangalam, Ashutosh K., Taneja, Veena, David, Chella S.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545203/
https://ncbi.nlm.nih.gov/pubmed/23293357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201891
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