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A New Humanized HLA Transgenic Mouse Model of Multiple Sclerosis Expressing Class II on Mouse CD4 T Cells

Among all the genetic factors associated with MS susceptibility, strongest association has been seen with expression of certain MHC class II molecules, although analysis of their exact function remains complicated. In general expression of class II is restricted to professional antigen presenting ce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mangalam, Ashutosh, Rodriguez, Moses, David, Chella
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266826/
https://ncbi.nlm.nih.gov/pubmed/17376829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1196/annals.1394.005
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