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Role of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic mice
Multiple sclerosis (MS), an inflammatory and demyelinating autoimmune disease of CNS has both, a genetic and an environmental predisposition. Among all the genetic factors associated with MS susceptibility, HLA-class II haplotypes such as DR2/DQ6, DR3/DQ2, and DR4/DQ8 show the strongest association....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173604/ https://ncbi.nlm.nih.gov/pubmed/21632210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2011.05.001 |
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