MLL fusion partner AF9 is an intrinsically disordered transcriptional regulator which recruits multiple partners via coupled folding and binding

Mixed Lineage Leukemia (MLL) fusion proteins cause oncogenic transformation of hematopoietic cells by constitutive recruitment of elongation factors to HOX promoters, resulting in over-expression of target genes. The structural basis of transactivation by MLL fusion partners remains undetermined. We...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Leach, Benjamin I, Kuntimaddi, Aravinda, Schmidt, Charles R, Cierpicki, Tomasz, Johnson, Stephanie A, Bushweller, John H.
格式: Artigo
語言:Inglês
出版: 2012
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545106/
https://ncbi.nlm.nih.gov/pubmed/23260655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.11.011
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍