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Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells

The cysteinyl leukotrienes (cys-LTs) LTC(4), LTD(4), and LTE(4) are a class of peptide-conjugated lipids formed from arachidonic acid and released during activation of mast cells (MCs). We now report that human cord-blood-derived MCs (hMCs) express the CysLT1 receptor, which responds not only to inf...

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Autori principali: Mellor, Elizabeth A., Maekawa, Akiko, Austen, K. Frank, Boyce, Joshua A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC35451/
https://ncbi.nlm.nih.gov/pubmed/11438743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.141221498
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