Cysteinyl Leukotrienes and Uridine Diphosphate Induce Cytokine Generation by Human Mast Cells Through an Interleukin 4–regulated Pathway that Is Inhibited by Leukotriene Receptor Antagonists

We previously reported that interleukin (IL)-4 upregulates the expression of leukotriene C(4) synthase (LTC(4)S) by human cord blood–derived mast cells (hMCs), augments their high-affinity Fc receptor for IgE (FcεRI)-dependent generation of eicosanoids and cytokines, and induces a calcium flux in re...

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Hlavní autoři: Mellor, Elizabeth A., Austen, K. Frank, Boyce, Joshua A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2002
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193768/
https://ncbi.nlm.nih.gov/pubmed/11877481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20020044
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