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PKCδ activation mediates angiogenesis via NADPH oxidase activity in PC-3 prostate cancer cells

BACKGROUND: PKCδ is generally known as a pro-apoptotic and anti-proliferative enzyme in human prostate cancer cells. METHODS: Here, we investigated the role of PKCδ on the growth of PC-3 human prostate cancer cells in vivo and in vitro. RESULTS: We found that sustained treatment with a specific PKCδ...

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Detalhes bibliográficos
Main Authors: Kim, Jeewon, Koyanagi, Tomoyoshi, Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544470/
https://ncbi.nlm.nih.gov/pubmed/21541971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21310
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