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Activating δPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats

Two pathways that have been shown to mediate cerebral ischemic damage are the MEK/ERK cascade and the pro-apoptotic δPKC pathway. We investigated the relationship between these pathways in a rat model of focal ischemia by observing and modifying the activation state of each pathway. The ERK1/2 inhib...

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Detalhes bibliográficos
Main Authors: Castañeda, Dora, Zhao, Heng, Mochly-Rosen, Daria, Steinberg, Gary K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746701/
https://ncbi.nlm.nih.gov/pubmed/19063870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.11.051
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