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Activating δPKC antagonizes the protective effect of ERK1/2 inhibition against stroke in rats
Two pathways that have been shown to mediate cerebral ischemic damage are the MEK/ERK cascade and the pro-apoptotic δPKC pathway. We investigated the relationship between these pathways in a rat model of focal ischemia by observing and modifying the activation state of each pathway. The ERK1/2 inhib...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2746701/ https://ncbi.nlm.nih.gov/pubmed/19063870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.11.051 |
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