Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC)

Inflammation and proinflammatory mediators are activators of δ-PKC. In vitro, δ-PKC regulates proinflammatory signaling in neutrophils and endothelial and epithelial cells, cells that can contribute to lung tissue damage associated with inflammation. In this study, a specific δ-PKC TAT peptide inhib...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Kilpatrick, Laurie E., Standage, Stephen W., Li, Haiying, Raj, Nichelle R., Korchak, Helen M., Wolfson, Marla R., Deutschman, Clifford S.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2011
Sujets:
Spotlight on Leading Edge Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004522/
https://ncbi.nlm.nih.gov/pubmed/20724665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0510281
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