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FAILED INTERLEUKIN-6 SIGNAL TRANSDUCTION IN MURINE SEPSIS: ATTENUTATION OF HEPATIC GLYCOPROTEIN (gp) 130 PHOSPHORYLATION
OBJECTIVE: Sepsis impairs the activation of the interleukin (IL)-6 dependent transcription factor signal transducer and activator of transcription (STAT)-3. However, the molecular basis for depressed functionality has not been characterized. In this study we test the hypothesis that altered signal t...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670954/ https://ncbi.nlm.nih.gov/pubmed/19325483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31819dee81 |
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