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FAILED INTERLEUKIN-6 SIGNAL TRANSDUCTION IN MURINE SEPSIS: ATTENUTATION OF HEPATIC GLYCOPROTEIN (gp) 130 PHOSPHORYLATION

OBJECTIVE: Sepsis impairs the activation of the interleukin (IL)-6 dependent transcription factor signal transducer and activator of transcription (STAT)-3. However, the molecular basis for depressed functionality has not been characterized. In this study we test the hypothesis that altered signal t...

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Detalhes bibliográficos
Main Authors: Abcejo, Arnoley S., Andrejko, Kenneth M., Raj, Nichelle R., Deutschman, Clifford S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670954/
https://ncbi.nlm.nih.gov/pubmed/19325483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31819dee81
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