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Transglutaminase inhibitors attenuate vascular calcification in a preclinical model
OBJECTIVE: In vitro, transglutaminase 2 (TG2)-mediated activation of the β-catenin signaling pathway is central in warfarin-induced calcification, warranting inquiry into the importance of this signaling axis as a target for preventive therapy of vascular calcification in vivo. METHODS AND RESULTS:...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544469/ https://ncbi.nlm.nih.gov/pubmed/23117658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300260 |
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