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Quercetin Attenuates Warfarin-induced Vascular Calcification in Vitro Independently from Matrix Gla Protein

Warfarin can stimulate vascular calcification in vitro via activation of β-catenin signaling and/or inhibition of matrix Gla protein (MGP) carboxylation. Calcification was induced in vascular smooth muscle cells (VSMCs) with therapeutic levels of warfarin in normal calcium and clinically acceptable...

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Detalhes bibliográficos
Main Authors: Beazley, Kelly E., Eghtesad, Saman, Nurminskaya, Maria V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554930/
https://ncbi.nlm.nih.gov/pubmed/23223575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.368639
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