Two Sides of MGP Null Arterial Disease: CHONDROGENIC LESIONS DEPENDENT ON TRANSGLUTAMINASE 2 AND ELASTIN FRAGMENTATION ASSOCIATED WITH INDUCTION OF ADIPSIN

Mutations in matrix Gla protein (MGP) have been correlated with vascular calcification. In the mouse model, MGP null vascular disease presents as calcifying cartilaginous lesions and mineral deposition along elastin lamellae (elastocalcinosis). Here we examined the mechanisms underlying both of thes...

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Autors principals: Beazley, Kelly E., Reckard, Steven, Nurminsky, Dmitry, Lima, Florence, Nurminskaya, Maria
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829453/
https://ncbi.nlm.nih.gov/pubmed/24036114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.495556
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