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Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations

Studies have suggested the potential importance of Notch signaling to the cancer stem cell population in some tumors, but it is not known whether all cells in the cancer stem cell fraction require Notch activity. To address this issue, we blocked Notch activity in MCF-7 cells by expressing a dominan...

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Autors principals: Wong, Nelson K Y, Fuller, Megan, Sung, Sandy, Wong, Fred, Karsan, Aly
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544441/
https://ncbi.nlm.nih.gov/pubmed/23342261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.18
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