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Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations

Studies have suggested the potential importance of Notch signaling to the cancer stem cell population in some tumors, but it is not known whether all cells in the cancer stem cell fraction require Notch activity. To address this issue, we blocked Notch activity in MCF-7 cells by expressing a dominan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wong, Nelson K Y, Fuller, Megan, Sung, Sandy, Wong, Fred, Karsan, Aly
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544441/
https://ncbi.nlm.nih.gov/pubmed/23342261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.18
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