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Heterogeneity of breast cancer stem cells as evidenced with Notch-dependent and Notch-independent populations

Studies have suggested the potential importance of Notch signaling to the cancer stem cell population in some tumors, but it is not known whether all cells in the cancer stem cell fraction require Notch activity. To address this issue, we blocked Notch activity in MCF-7 cells by expressing a dominan...

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Détails bibliographiques
Auteurs principaux: Wong, Nelson K Y, Fuller, Megan, Sung, Sandy, Wong, Fred, Karsan, Aly
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544441/
https://ncbi.nlm.nih.gov/pubmed/23342261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.18
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