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Inhibition of Histone Deacetylases 1 and 3 Protects Injured Retinal Ganglion Cells

PURPOSE. Thy-1 is a marker of retinal ganglion cell (RGC) differentiation. Optic nerve injury triggers reduction of Thy-1 promoter activation followed by retinal ganglion cell (RGC) death. This study determined whether MS-275, an inhibitor of the histone deacetylases 1 and 3, can inhibit these chang...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Chindasub, Panida, Lindsey, James D., Duong-Polk, Karen, Leung, Christopher K., Weinreb, Robert N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Association for Research in Vision and Ophthalmology 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544425/
https://ncbi.nlm.nih.gov/pubmed/23197683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10850
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