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Inhibition of Histone Deacetylases 1 and 3 Protects Injured Retinal Ganglion Cells
PURPOSE. Thy-1 is a marker of retinal ganglion cell (RGC) differentiation. Optic nerve injury triggers reduction of Thy-1 promoter activation followed by retinal ganglion cell (RGC) death. This study determined whether MS-275, an inhibitor of the histone deacetylases 1 and 3, can inhibit these chang...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3544425/ https://ncbi.nlm.nih.gov/pubmed/23197683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10850 |
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