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DNA Ligase-Mediated Translation of DNA Into Densely Functionalized Nucleic Acid Polymers

[Image: see text] We developed a method to translate DNA sequences into densely functionalized nucleic acids by using T4 DNA ligase to mediate the DNA-templated polymerization of 5′-phosphorylated trinucleotides containing a wide variety of appended functional groups. This polymerization proceeds se...

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Detalhes bibliográficos
Main Authors: Hili, Ryan, Niu, Jia, Liu, David R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544274/
https://ncbi.nlm.nih.gov/pubmed/23256841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311331m
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