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P2X7 receptor in epilepsy; role in pathophysiology and potential targeting for seizure control

The P2X7 receptor is an ATP-gated non-selective cation-permeable ionotropic receptor selectively expressed in neurons and glia in the brain. Activation of the P2X7 receptor has been found to modulate neuronal excitability in the hippocampus and it has also been linked to microglia activation and neu...

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Autors principals: Engel, Tobias, Jimenez-Pacheco, Alba, Miras-Portugal, Maria Teresa, Diaz-Hernandez, Miguel, Henshall, David C
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3544219/
https://ncbi.nlm.nih.gov/pubmed/23320131
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