Impact of site-specific phosphorylation of protein kinase A sites Ser(23) and Ser(24) of cardiac troponin I in human cardiomyocytes

PKA-mediated phosphorylation of contractile proteins upon β-adrenergic stimulation plays an important role in the regulation of cardiac performance. Phosphorylation of the PKA sites (Ser(23)/Ser(24)) of cardiac troponin (cTn)I results in a decrease in myofilament Ca(2+) sensitivity and an increase i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Wijnker, Paul J. M., Foster, D. Brian, Tsao, Allison L., Frazier, Aisha H., dos Remedios, Cristobal G., Murphy, Anne M., Stienen, Ger J. M., van der Velden, Jolanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Muscle Mechanics and Ventricular Function
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543672/
https://ncbi.nlm.nih.gov/pubmed/23144315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00498.2012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados