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Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1

Colonic chloride secretion is regulated via the neurohormonal and immune systems. Exogenous chemicals (e.g., butyrate, propionate) can affect chloride secretion. Capsaicin, the pungent ingredient of the chili peppers, exerts various effects on gastrointestinal function. Capsaicin is known to activat...

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Bibliografiske detaljer
Main Authors: Bouyer, Patrice G., Tang, Xu, Weber, Christopher R., Shen, Le, Turner, Jerrold R., Matthews, Jeffrey B.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543646/
https://ncbi.nlm.nih.gov/pubmed/23139219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00483.2011
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