NKCC1 and NKCC2: The pathogenetic role of cation-chloride cotransporters in hypertension

This review summarizes the data on the functional significance of ubiquitous (NKCC1) and renal-specific (NKCC2) isoforms of electroneutral sodium, potassium and chloride cotransporters. These carriers contribute to the pathogenesis of hypertension via regulation of intracellular chloride concentrati...

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Bibliographic Details
Published in:Genes Dis
Main Authors: Orlov, Sergei N., Koltsova, Svetlana V., Kapilevich, Leonid V., Gusakova, Svetlana V., Dulin, Nickolai O.
Format: Artigo
Language:Inglês
Published: Chongqing Medical University 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4477834/
https://ncbi.nlm.nih.gov/pubmed/26114157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gendis.2015.02.007
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