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The Developmental Regulator Pax6 Is Essential for Maintenance of Islet Cell Function in the Adult Mouse Pancreas

The transcription factor Pax6 is a developmental regulator with a crucial role in development of the eye, brain, and olfactory system. Pax6 is also required for correct development of the endocrine pancreas and specification of hormone producing endocrine cell types. Glucagon-producing cells are alm...

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Main Authors: Hart, Alan W., Mella, Sebastien, Mendrychowski, Jacek, van Heyningen, Veronica, Kleinjan, Dirk A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543312/
https://ncbi.nlm.nih.gov/pubmed/23326594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054173
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