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The Developmental Regulator Pax6 Is Essential for Maintenance of Islet Cell Function in the Adult Mouse Pancreas

The transcription factor Pax6 is a developmental regulator with a crucial role in development of the eye, brain, and olfactory system. Pax6 is also required for correct development of the endocrine pancreas and specification of hormone producing endocrine cell types. Glucagon-producing cells are alm...

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Detaylı Bibliyografya
Asıl Yazarlar: Hart, Alan W., Mella, Sebastien, Mendrychowski, Jacek, van Heyningen, Veronica, Kleinjan, Dirk A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543312/
https://ncbi.nlm.nih.gov/pubmed/23326594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054173
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