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The Level of the Transcription Factor Pax6 Is Essential for Controlling the Balance between Neural Stem Cell Self-Renewal and Neurogenesis

Neural stem cell self-renewal, neurogenesis, and cell fate determination are processes that control the generation of specific classes of neurons at the correct place and time. The transcription factor Pax6 is essential for neural stem cell proliferation, multipotency, and neurogenesis in many regio...

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Detalhes bibliográficos
Principais autores: Sansom, Stephen N., Griffiths, Dean S., Faedo, Andrea, Kleinjan, Dirk-Jan, Ruan, Youlin, Smith, James, van Heyningen, Veronica, Rubenstein, John L., Livesey, Frederick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686252/
https://ncbi.nlm.nih.gov/pubmed/19521500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000511
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