Neuropeptide deficient mice have attenuated nociceptive, vascular, and inflammatory changes in a tibia fracture model of complex regional pain syndrome

BACKGROUND: Distal limb fracture in man can induce a complex regional pain syndrome (CRPS) with pain, warmth, edema, and cutaneous inflammation. In the present study substance P (SP, Tac1(−/−)) and CGRP receptor (RAMP1(−/−)) deficient mice were used to investigate the contribution of neuropeptide si...

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Autors principals: Guo, Tian-Zhi, Wei, Tzuping, Shi, Xiaoyou, Li, Wen-Wu, Hou, Saiyun, Wang, Liping, Tsujikawa, Kazutake, Rice, Kenner C, Cheng, Kejun, Clark, David J, Kingery, Wade S
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543283/
https://ncbi.nlm.nih.gov/pubmed/23191958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-8-85
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