Biphasic Regulation of Myosin Light Chain Phosphorylation by p21-activated Kinase Modulates Intestinal Smooth Muscle Contractility

Supraphysiological mechanical stretching in smooth muscle results in decreased contractile activity. However, the mechanism is unclear. Previous studies indicated that intestinal motility dysfunction after edema development is associated with increased smooth muscle stress and decreased myosin light...

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Détails bibliographiques
Auteurs principaux: Chu, Ji, Pham, Ngoc T., Olate, Nicole, Kislitsyna, Karina, Day, Mary-Clare, LeTourneau, Phillip A., Kots, Alexander, Stewart, Randolph H., Laine, Glen A., Cox, Charles S., Uray, Karen
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Molecular Bases of Disease
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3543003/
https://ncbi.nlm.nih.gov/pubmed/23161543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370718
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